Stuart Little is a 1945 American children's novel by E.B. White. It was White's first children's book, and it is now widely recognized as a classic in children's literature. Stuart Little was illustrated by the subsequently award-winning artist Garth Williams, also his first work for children. The book is a realistic yet fantastical story about a mouse-like human boy named “Stuart Little.” According to the first chapter, he looked very much like a mouse in every way.
In a letter White wrote in response to inquiries from readers, he described how he came to conceive of Stuart Little: "Many years ago, I went to bed one night in a railway sleeping car, and during the night I dreamed about a tiny boy who acted rather like a rat. That's how the story of Stuart Little got started." He had the dream in the spring of 1926 while sleeping on a train on his way back to New York from a visit to the Shenandoah Valley.
White typed up a few stories about “Stuart,” which he told to his eighteen nieces and nephews when they asked him to tell them a story. In 1935 White's wife, Katharine, showed these stories to Clarence Day, then a regular contributor to The New Yorker. Day liked the stories and encouraged White not to neglect them, but neither Oxford University Press nor Viking Press was interested in the stories, and White did not immediately develop them further.